We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.
Medicine

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

What Is Pramipexole?

Tricia Christensen
By
Updated: May 17, 2024
Views: 4,638
Share

Pramipexole, which is widely known by its trade name, Mirapex®, is a medication manufactured by Boehringer Ingelham Pharmaceuticals®. It is a dopamine agonist, which means it stimulates some of the dopamine receptors by binding to them, essentially replicating the action of dopamine in the body. The uses of this medication are multiple, but it is recognized mostly as a medication to treat Restless Legs Syndrome (RLS) and Parkinson’s disease in early stages, or occasionally late stages. Established off-label uses include for cluster headaches and sexual dysfunction arising from medications that treat depression. Like all medications, pramipexole has both benefits and side effects.

Mirapex® is generally given orally, and specific dosage can depend on the condition being treated. Since pramipexole comes in both a regular and extended release form, dose within conditions can also vary. Often, this medication begins with a smaller dose that increases over a week or two. For Parkinson’s disease total dose tends not to exceed 4.5 mg per day, and for RLS, dose is much smaller, usually not larger than half a milligram per day.

There are a few people who may be at greater risk for complications if they take pramipexole. The safety of the medicine has not be proven for the fetus or nursing infant, so pregnant or nursing mothers may want to avoid this medication. Sometimes low blood pressure, movement disorders, or diseases of the kidney call for changing dose. Patients who have sexual or gambling addiction could be at greater risk taking pramipexole because a high number of anecdotal reports suggest the drug may fuel certain compulsivity conditions, even if a person had no problems with these issues prior to taking medication. Additionally, elderly patients need careful observation while using Mirapex® because they are more prone to developing side effects like hallucinations.

Some of the common and more benign side effects associated with pramipexole, which not all users develop, include tiredness, drowsiness, forgetfulness, sexual dysfunction, water retention in the lower limbs and feet, stomach upset, changes in bowel movements, dizziness, headache, loss of appetite, and vision problems. More serious side effects that require immediate medical attention include anaphylaxis or severe allergic response to the medication, hallucinations, increase in involuntary movements, anorexia, extreme nausea accompanied by perspiration and fainting, arrythmias, and bouts of unintended sleeping. Though occurring rarely, compulsive gambling, shopping, eating, and et cetera are also serious and should be reported to a doctor by the patient or caregivers.

Pramipexole may need dose adjustment or may be the wrong choice when patients take other medications. The drug can interact with a wide variety of medications and patients should have a list of all drugs, including over the counter ones and herbal or vitamin supplements, that they can give to their doctors before accepting any new prescriptions. Patients are also advised not to discontinue the medication abruptly as this may cause side effects. Tapering off the medication slowly is recommended.

Share
WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Tricia Christensen
By Tricia Christensen
With a Literature degree from Sonoma State University and years of experience as a WiseGeek contributor, Tricia Christensen is based in Northern California and brings a wealth of knowledge and passion to her writing. Her wide-ranging interests include reading, writing, medicine, art, film, history, politics, ethics, and religion, all of which she incorporates into her informative articles. Tricia is currently working on her first novel.

Editors' Picks

Discussion Comments
Tricia Christensen
Tricia Christensen
With a Literature degree from Sonoma State University and years of experience as a WiseGeek contributor, Tricia...
Learn more
Share
https://www.wisegeek.net/what-is-pramipexole.htm
Copy this link
WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.