We are independent & ad-supported. We may earn a commission for purchases made through our links.

Advertiser Disclosure

Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.

How We Make Money

We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently from our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What Is Hydrocodone with Ibuprofen?

By Jacquelyn Gilchrist
Updated May 17, 2024
Our promise to you
WiseGEEK is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At WiseGEEK, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Hydrocodone with ibuprofen is a medication prescribed to treat moderate to severe pain. It is intended for short-term use only. This drug is a combination of two medicines: hydrocodone and ibuprofen. The former drug is a narcotic pain reliever, while the latter is a nonsteroidal anti-inflammatory drug (NSAID). Together, they work to alleviate pain and inflammation by acting on certain areas of the brain.

Adults are typically prescribed a dose every four to six hours; however, they may not exceed five tablets in any 24-hour time period. Patients should take this medication with a full glass of water, and should continue to drink plenty of water throughout the day. If stomach upset occurs, the doctor may approve the consumption of a snack with each dose. The patient should avoid lying down for 30 minutes following each dose. Hydrocodone with ibuprofen is not usually prescribed for longer than 10 days.

Patients should be aware that hydrocodone with ibuprofen is potentially habit-forming. Some people may experience withdrawal symptoms when discontinuing the drug, such as irritability, restlessness, and anxiety. Sweating, runny nose, and watery eyes can also occur. The doctor will likely recommend decreasing the drug for awhile before completely discontinuing it.

Some side effects may occur with the use of hydrocodone with ibuprofen, which should be reported to the prescribing physician if they become severe. Patients may experience dizziness, drowsiness, and constipation. Nausea, vomiting, and stomach upset have also been reported, as well as a dry mouth. Those who suffer from constipation should consult a doctor before taking a laxative.

More serious side effects require immediate medical attention. Rarely, patients have experienced liver disease, which may become fatal. This may be indicated by jaundice, dark urine, and persistent nausea or vomiting. It can also cause severe stomach pain and unusual fatigue.

Other serious side effects from hydrocodone with ibuprofen may include vision changes, mood changes, and ringing in the ears or other hearing changes. Fainting, rapid or irregular heartbeat, and shallow breathing have also been reported. An unexplained stiff neck, seizures, and swelling of the hands or feet may occur.

Before using hydrocodone with ibuprofen to alleviate pain, patients must disclose their other medical conditions, medications, and supplements. It is strongly recommended that women who are breastfeeding or pregnant avoid this drug whenever possible. Hydrocodone with ibuprofen may be contraindicated for use by those who have poorly controlled diabetes, severe breathing problems, or a history of drug or alcohol abuse. This medication may interact with other drugs, such as certain antidepressants, corticosteroids, and other pain relievers.

WiseGEEK is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.

Discussion Comments

WiseGEEK, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGEEK, in your inbox

Our latest articles, guides, and more, delivered daily.