We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.
Medicine

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

What is Efavirenz?

By Melissa Barrett
Updated: May 17, 2024
Views: 3,771
Share

Efavirenz is a medication that is used to treat the human immunodeficiency virus (HIV) by slowing the reproduction of the virus. It is very rarely used alone and is often prescribed with medicines such as tenofovir and emtricitabine as part of a highly active artiretroviral therepy (HAART). Efavirenz can also be combined with other antiretroviral drugs to help prevent HIV infection in healthcare workers who have been exposed to the virus through accidental needle-sticks.

Common side effects of efavirenz include upset stomach, headache, forgetfulness and insomnia. Mood changes, confusion and depression may also occur soon after beginning treatment. Usually these side effects diminish or disappear entirely over time. More serious side effects, such as blistering skin, psychosis and seizures, require immediate medical attention. This class of medicine can affect liver function, so visible signs of jaundice, such as yellowing of the whites of the eyes or skin, should be reported to a physician immediately.

Efavirenz can cause birth defects, especially when taken by a woman during the first trimester of her pregnancy. The medication can also reduce the effectiveness of hormonal birth control medicines. When using this medication, sexually active women should use condoms or a diaphragm to prevent pregnancy and should notify their doctor immediately if they think they might be pregnant. Women on efavirenz should not breastfeed.

Other prescription medicines, herbal supplements and over-the-counter medications can interact adversely with efavirenz. Some blood thinners and anti-depressants can interfere with the medicine’s effectiveness or increase its side effects. Over-the-counter medications might need to be restricted during treatment, because they can add extra stress to the liver. The use of herbal supplements, especially ones containing St. John’s wort, should be reduced or eliminated.

Normal dosing in adults is 600-800 milligrams a day, and it generally is taken once a day in pill or capsule form. Most of the psychological side effects occur within a few hours of taking the medication, so it is often suggested that it be taken at night. That way a patient can often sleep through the worst of the adverse effects.

Share
WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.

Editors' Picks

Discussion Comments
Share
https://www.wisegeek.net/what-is-efavirenz.htm
Copy this link
WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.