Classified as an angiotensin receptor blocker, candesartan cilexetil helps control high blood pressure. Known as an AT1 subtype angiotensin II receptor antagonist, the drug works by blocking the ability of the chemical angiotensin II to raise blood pressure within the body. Angiotensin II naturally constricts the veins and arteries of the body. When candesartan is administered, the chemical is unsuccessful at causing vessel or artery constriction; this helps to lower the body's blood pressure. Its administration successfully relaxes the blood vessels within the body.
The drug is also prescribed to patients suffering from congestive heart failure. It works to help lessen the strain of the heart's workload, which enables it to efficiently pump more easily. Patients with congestive heart failure who are prescribed the drug often have a lower loss of life and fewer hospitalizations than those not prescribed candesartan. Patients with type 2 diabetes are often prescribed candesartan to help treat kidney disorders and prevent other damage resulting from type 2 diabetes.
Approved by the U.S. Food and Drug Administration (FDA) in 1988, cadesartan holds a category D classification. It can cause harm or death to unborn babies if ingested during the second or third trimester of a pregnancy. It has not been determined if the drug can pass into breast milk and be passed on to a nursing baby.
A slow-acting drug, the patient may not see a lowering of high blood pressure for two to four weeks. Users should not cease taking the drug unless advised to by a physician, because all symptoms will return. The medication is not a cure; it's only a treatment.
Users taking candesartan may notice dizziness, lower blood pressure and an increase in upper respiratory infections. Suffers of congestive heart failure may have high blood potassium levels. Severe reactions may include hives, difficulty breathing, severe dizziness and swelling of the face, throat or tongue. The drug can cause a breakdown of skeletal muscle tissue and kidney failure. Users should watch for muscle weakness, dark urine, swelling of the feet or hands, and nausea or vomiting.
Available in tablet form, candesartan is usually taken once or twice a day. The drug is often prescribed in conjunction with an angiotensin-converting enzyme (ACE) inhibitor, which appears to help increase both drugs' effectiveness. Avoid drinking alcohol while taking the medication. Alcohol lowers blood pressure, which can cause side effects to occur when used in conjunction with the medication.
