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What Is a Chondroitin Glucosamine Complex?

By Andrea Cross
Updated May 17, 2024
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Chondroitin glucosamine complex is a health supplement that combines chondroitin sulfate and glucosamine. The supplement is often used to treat osteoarthritis and inflammatory joint disorders and to improve general joint health. This complex is marketed as an herbal supplement and is available in tablet, capsule, liquid, and powder forms. Care still must be taken when using it, however, as like most treatments, it has side effects and contraindications. Further, its effectiveness is under debate.

These two elements occur naturally in the cartilage of the joints but can reduce over time due to diseases such as arthritis and normal wear and tear. This is especially relevant to weight-bearing joints such as the hips and knees. The cartilage becomes compressed and can no longer regenerate as effectively. Chondroitin glucosamine complex is taken to help the cartilage regenerate and to prevent further degradation. It is also thought to act as an anti-inflammatory.

Glucosamine, also called chitosamine, is a sugar protein. The form used in chondroitin glucosamine complex often comes from shellfish as it is a major component of their shells. It is readily absorbed by the body and helps to keep the joints flexible. Chondroitin sulfate consists of sugar chains and helps joints to maintain synovial fluid. This subsequently helps to lubricate the joints, making them more elastic and resilient.

Even though chondroitin glucosamine complex is considered an herbal supplement, it still has potential side effects. Mild side effects can include nausea, heartburn, and diarrhea. Serious side effects that require medical attention may include swelling of the face, including the tongue and lips, hives, and shortness of breath.

Chondroitin glucosamine complex should also be avoided if certain other medical conditions are present. If a person has diabetes, he or she should avoid the supplement as the chondroitin and glucosamine are both sugar based and can result in an increase in blood sugar. It can also reduce the effect of insulin treatment.

Individuals who are taking chitosan, a weight-loss drug, should also avoid the complex, as the glucosamine will not be readily absorbed. Other situations where the product should be avoided include people who are taking warfarin for blood-clotting disorders, who are allergic to shellfish, and who are following a low-sodium diet. Vegans and vegetarians may also want to avoid the supplement as they are often animal based.

The actual effect of taking chondroitin glucosamine complex is debatable. Studies have been carried out to try to determine its effects, but most are considered to be unreliable. Caution must also be taken to buy the product from a reputable source because the manufacture of herbal supplements is not well regulated.

WiseGEEK is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.

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