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What Factors Affect a Sufficient Ofloxacin Dose?

By B. Chisholm
Updated: May 17, 2024
Views: 3,411
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The main factors that affect the sufficient ofloxacin dose depends on the condition being treated, tolerance of the patient, and the preparation being used. Ofloxacin is an antibiotic medicine used to treat a number of bacterial infections. In most countries it is available by prescription only. It is available in various pharmaceutical forms, including oral preparations, injectables and eye drops, and may be known by different trade names in different countries, according to manufacturer.

Ofloxacin belongs to the antibiotic class called fluoroquinolones. They work by inhibiting an enzyme in the bacteria which is involved in the production of bacterial DNA, thus essentially killing the bacteria. Ofloxacin may be used to treat many infections including those of the urinary tract, respiratory tract, prostate and gonorrhea. Resistance to ofloxacin has been found in some organisms so a sample may be taken from the patient for culture in the lab to ensure sensitivity.

The most important factor influencing the ofloxacin dose is the condition being treated. For less severe, or uncomplicated, infections of the urinary tract, lower doses may be used for shorter periods, increasing if more severe, or if the infection is affecting the urinary tract higher up. For respiratory tract infections a higher dose is used. In these infections the ofloxacin dose is usually taken twice a day. When treating gonorrhea, the ofloxacin dose is given as a single one, although in some countries this is no longer a recommended treatment, due to resistance.

The correct ofloxacin dose will be determined by the treating doctor and should be followed closely, both the dose and the dosing schedule, to ensure maximum effectiveness. Even if symptoms resolve, the full course of any antibiotic must be completed. Failure to do so may result in the development of resistance and difficulty in treating infections at a later stage.

As with any medication, regardless of the dose, ofloxacin may interact with other medications and be contraindicated in patients with some underlying conditions. These should all be discussed with the prescribing doctor, including homeopathic, over-the-counter and complementary medicines. Pregnancy, desired pregnancy and lactation should also be discussed.

When taking a course of ofloxacin for a bacterial infection, unwanted side effects may occur. Commonly reported side effects include gastrointestinal issues such as nausea, vomiting and diarrhea, headache, dizziness and drowsiness. Caution when driving and handling heavy machinery is recommended while taking ofloxacin. Should severe adverse effects occur, medical help should be sought.

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