Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI) anti-depressant used in the treatment of depression and some anxiety disorders, particularly obsessive-compulsive disorder. It is effective for many people at easing the symptoms of these disorders, but it does have several common side effects as well as some rare serious ones. Patients should be aware of the common and potentially serious effects, and should not hesitate to ask a doctor about any concerns surrounding fluvoxamine side effects.
Many people experience none of the possible side effects from fluvoxamine or experience them for only a short time while the body adjusts. It is important to balance the effectiveness of the drug at reducing the symptoms of the disorder with the side effects a patient experiences. Some side effects will be intolerable for one patient but not significantly troublesome for another, particularly if the drug is very effective. Alcohol consumption and some over the counter medications, such as cold and flu medicine, can increase the side effects of fluvoxamine.
Problems with the gastrointestinal tract are common, such as nausea, vomiting, loss of appetite, gas or bloating, constipation, or diarrhea. Some patients experience sexual problems, such as difficulty reaching orgasm or decreased libido. Other common side effects include headache, dry mouth, changes in the way things taste, sweating, weakness, agitation or nervousness, and difficulty sleeping. Sedation and/or dizziness is another one of the fluvoxamine side effects that may be experienced, especially when treatment has just started. Patients should avoid driving, operating machinery, or engaging in other activities that require total concentration until the sedative effect passes or the medication has been taken long enough that sedation can be dismissed as a side effect.
There are some rare serious fluvoxamine side effects that may be encountered, and patients should always seek medical attention for them. Allergic reactions are possible, including abnormal swelling, itching, difficulty breathing, or rash. Patients may potentially experience seizures or problems with coordination or movement. In rare cases, emotional disturbances, such as heightened anxiety, irritability, restlessness, aggression or hostility, or depression can occur. Some patients experience hallucinations or strange thoughts, including persistent thoughts of suicide or self harm.
If the fluvoxamine side effects experienced by a particular patient are among the common side effects, changing the dosage or merely waiting a few weeks for the body to get used to the medication often reduces or eliminates the side effects. Serious fluvoxamine side effects will usually lead to discontinuation of the medication. Patients should always ask a medical professional about any side effects that are concerning, but should not discontinue fluvoxamine suddenly or without the guidance of a doctor.