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What Are the Most Common Aminoglycoside Side Effects?

By Lauren Romano
Updated May 17, 2024
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Aminoglycosides are antibiotics that treat antibacterial infections and are administered primarily through injection, but may also be done through irrigation or inhalation; their job is to kill bacteria or prevent the growth of it. The most common side effects involve the head or stomach area, although some happen throughout the rest of the body. Certain side effects may seem minute, but are actually signs of an allergic reaction and require immediate medical attention. Although it doesn't always happen, some may experience side effects after going off the medication. Some side effects seem common but are actually rare.

The most common aminoglycoside side effects involve the head area. The patient may experience dizziness, headaches, hearing loss or ringing in the ears. When using streptomycin, patients may experience burning or numbness in the face or mouth. In the stomach area, the most common side effects include nausea, vomiting and loss of appetite. There may also be decreased or increased urine output.

Signs of an allergic reaction may seem insignificant, as though they would be simple side effects and nothing more. Itching, hives and a skin rash are all signs of a possible allergic reaction to the medicine. At the first indication of any of these, it's vital to see a medical professional.

There are also aminoglycoside side effects that can continue after going off the medication. They can include hearing loss, dizziness and buzzing in the ears. Some may experience nausea or vomiting, loss of appetite and feeling unsteady. It's important to consult a doctor upon noticing these side effects after stopping the medication.

Some aminoglycoside side effects seem common but are actually rare and should be brought to the attention of a medical professional. Drowsiness, feeling weak and having trouble breathing are some of the side effects to pay extra attention to. Note any loss of vision while taking streptomycin, or fever, chills or spasms while taking gentamicin.

Although some aminoglycoside side effects are considered common, it's still important to seek medical treatment if they get progressively worse or continue for a long period of time. Talk to a doctor if any aminoglycoside side effects don't seem common or differ from the standard ones that have already been experienced. Each person reacts differently to medications, so to keep track of the individual side effects, it's best to keep a written account of them on a daily basis.

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