We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.
Medicine

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

How Effective Is Glyburide for Diabetes?

By B. Chisholm
Updated: May 17, 2024
Views: 4,155
Share

Glyburide for diabetes is effective as a treatment. It is used either alone, or in combination with other medication to treat Type 2 diabetes which does not respond to dietary changes alone. Glyburide belongs to the class of drugs called sulphonylureas, which includes glibenclamide and gliclazide, and is usually available by prescription only. It is known by different trade names in different countries, according to the manufacturer.

Type 2 diabetes is a disease in which the glucose levels in the blood are too high. This happens due to the fact that either there is insufficient insulin due to low production by the pancreas, or the cells of the body are resistant to the insulin produced (insulin resistance). Insulin is a chemical which is responsible for controlling the sensitive balance of glucose in the body. If left untreated, diabetes can have serious and severe long-term effects.

Obesity is one of the main risk factors for Type 2 diabetes and lifestyle changes and weight loss are the first steps in treatment. These lifestyle changes and loss of weight may not be sufficient to control blood sugar and therefore drugs may need to given in addition to the non-drug measures. Glyburide for diabetes is one of the drugs which may be used. It may be used alone, or in combination with another class of diabetic drug, such as a biguanide like metformin.

The mechanism of action of glyburide for diabetes is stimulation of the release of insulin from the pancreas. This means that glyburide for diabetes will work only in patients who still have some pancreatic responsiveness. The prescribing doctor will monitor response and, if necessary, change dose, add another drug or change the class of drug.

The side effects of glyburide for diabetes may include hypoglycemia, or low blood sugar, headache, dizziness and gastrointestinal side effects. Should any adverse effects occur, they should be discussed with the prescribing doctor. As with any medication, glyburide may interact with other medications so these, including over-the-counter, homeopathic and complementary medications, should be disclosed to the prescribing doctor before starting treatment. Pregnancy, desired pregnancy and lactation should also be discussed.

The glyburide dosage will be determined by the doctor and is usually started at a low dose and titrated up slowly with close monitoring of the patient's blood glucose levels. Glyburide dosage will be adjusted according to tolerance and response and the prescribed dose should never be exceeded due to the risk of hypoglycemia. It may be given as a single daily dose or divided doses.

Share
WiseGeek is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.

Editors' Picks

Discussion Comments
Share
https://www.wisegeek.net/how-effective-is-glyburide-for-diabetes.htm
Copy this link
WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.

WiseGeek, in your inbox

Our latest articles, guides, and more, delivered daily.